منابع مشابه
Trovatore: Towards a Highly Scalable Distributed Web Crawler
Trovatore is an ongoing project aimed at realizing an efficient distributed and highly scalable web crawler. This poster illustrates the main ideas behind its design.
متن کاملThe roles of IL-2, IL-7, and IL15 Ligands in B Cells development
Abstract Background B cells play an important role in the immune system due to production of the immunoglobulin and secreting several cytokines. It has been shown that B cells produced successfully in the presence of stem cell factor (SCF) and Flt3 ligand (Flt3L). IL2, IL7, and IL15 cytokines as -common family have an essential cytokines may support either synergistically or in an additive m...
متن کاملGinger Extract Reduces the Expression of IL-17 and IL-23 in the Seraand Central Nervous System of EAEMice
Background: IL-17/IL-23 axis plays an important role in the pathogenesis of several autoimmune diseases such as experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS). The immunomodulatory properties of ginger are reported in previous studies. Objective: To evaluate the effects of ginger extract on the expression of IL-17 and IL-23 in a model of EAE. Methods: EAE was induc...
متن کاملVitamin D Modulates the Expression of IL-27 and IL-33 in the Central Nervous System in Experimental Autoimmune Encephalomyelitis
Background: It has been reported that vitamin D has broad anti-inflammatory and immunomodulatory effects. Objective: To evaluate the effects of vitamin D on the expression of IL-27 and IL-33 in a model of experimental autoimmune encephalomyelitis (EAE). Methods: EAE was induced in C57BL/6 mice by immunization with myelin oligodendroglial glycoprotein mixed with complete Freund's adjuvant. The m...
متن کاملTargeting the IL-12/IL-23 axis
Combination immune checkpoint blockade has demonstrated significant clinical responses in cancers infiltrated by T cells. Many tumors contain high proportions of myeloid cells and these can secrete immunosuppressive cytokines like IL-23. Our data suggest the clinical potential of using anti-CD40 (push) and anti-IL-23 mAbs (pull) to tip the IL-12/23 balance in established tumors and act as an al...
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ژورنال
عنوان ژورنال: The Musical Times and Singing Class Circular
سال: 1871
ISSN: 0958-8434
DOI: 10.2307/3351946